A Novel Biochemical Formula of Dissolvable Micro-Needles Designed to Manage Type 2 Diabetes


Researchers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) of National Institutes of Health (NIH) have invented a biochemically composed patch of dissolving micro needles in order to treat the Type 2 Diabetes. The biochemical patch containing mineralized compounds responds to blood chemistry to regulate the body glucose automatically.

After examining the proof-of-concept findings performed on mice, the team of researchers proved that the chemicals use to interact with blood stream to manage blood sugar in the body for days at the same time.

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Richard D. Leapman, Ph.D. Senior Investigator and scientific director at NIBIB said in a statement that, “This experimental approach could be a way to take advantage of the fact that persons with type 2 diabetes can still produce some insulin. A weekly microneedle patch application would also be less complicated and painful than routines that require frequent blood testing.”

The hormone produced in the pancreas, i.e. insulin is secreted in the blood stream to control glucose with intent to respond to consumed foods. it is very essential to transfer glucose from blood streams in to body cells where sugar gets converted into energy or saved.

Type 2 Diabetes is generally detected in teenagers and young adults, in which body becomes not able to produce insulin at all. the disease if not treated well or ignored, it can affect both nerve and vascular damage all through the body along with the debilitating effects on heart, kidneys, eyes and feet.

The team of researchers led by the Chief Investigator, Xiaoyuan (Shawn) Chen from the Laboratory of Molecular Imaging and Nanomedicine at NIBIB, is examining the alternate therapy approach to control blood sugar levels with the help of painless skin patch to manage type 2 diabetes.

Chen said that, “Alginate is a pliable material — it is soft, but not too soft. It has to be able to poke the dermis, and while not a commonly used material for needles, it seems to work pretty well in this case.”